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Conference ·
MRI findings in progressive multiple sclerosis
A clinical overview of what brain and spinal-cord MRI reveal about progression and treatment trials.
ICTRIMS · New Delhi, India
- Delivered
- Event
- ICTRIMS
- Place
- New Delhi, India
- Format
- Conference
- Source deck
- 35 slides
From the slides
Deck notes
This ICTRIMS lecture traced MRI findings in progressive multiple sclerosis from clinical phenotypes to quantitative measures of brain and spinal-cord change. It placed those measures in the context of treatment trials.
The question
What can MRI reveal about progression beyond the clinical labels used to describe multiple sclerosis?
Deck outline
- The clinical description of progressive multiple sclerosis
- Brain atrophy and percentage brain-volume change
- Data-driven MRI subtypes
- Evidence from treatment trials
- Spinal-cord atrophy and disability
- Clinical utility and targets for progression
Take-away
Brain and spinal-cord measures capture complementary aspects of progression, but their value rests on a clear connection to disability and treatment outcomes.