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Debate ·
MRI phenotypes will replace clinical phenotypes in multiple sclerosis — Pro
A debate case for using MRI-derived patterns to describe multiple sclerosis beyond conventional clinical labels.
Advanced MRI Milan · Milan, Italy
- Delivered
- Event
- Advanced MRI Milan
- Place
- Milan, Italy
- Format
- Debate
- Source deck
- 19 slides
From the slides
Deck notes
This debate contribution made the case for MRI-derived phenotypes in multiple sclerosis. It set conventional clinical labels against spatial patterns of atrophy and data-driven disease subtypes.
The question
Can MRI reveal clinically useful disease structure that is hidden by relapse- and progression-based labels?
Deck outline
- Heterogeneity within multiple sclerosis
- The limits of conventional disease classification
- Regional patterns of grey-matter atrophy
- Data-driven MRI subtypes and their evolution
- Associations between MRI patterns and disability risk
- Points for discussion
Take-away
MRI patterns can expose meaningful differences between patients that broad clinical phenotypes do not capture, making them useful for stratification.